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Dental stem cell and dental tissue regeneration

Qiming Zhai, Zhiwei Dong, Wei Wang, Bei Li, Yan Jin

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 152-159 doi: 10.1007/s11684-018-0628-x

Abstract: the development of tooth germ tissue located in the jaw and consist of the enamel, dentin, cementum, pulpThese characteristics, to a certain extent, greatly complicate the research in tooth regeneration.Recently, new ideas for tooth and tissue regeneration have begun to appear with rapid developments in), stem cells isolated from human pulp of exfoliated deciduous teeth (SHED), periodontal ligament stemThis review outlines the cell types and strategies of stem cell therapy applied in tooth regeneration

Keywords： stem cells     pulp regeneration     periodontal regeneration    

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Self-etching adhesives: possible new pulp capping agents to vital pulp therapy

Chun CUI, Xiu-Neng ZHOU, Wei-Min CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 77-79 doi: 10.1007/s11684-010-0104-8

Abstract:

Pulp capping is one of the solving for keeping vital pulp in the case of dentin caries, reversiblepulpitis or traumatic pulp exposure.The presence of bacteria on the cavity walls or in the pulp was the major factor that leads to the failureof pulp capping.Traditional pulp capping agent, calcium hydroxide, may not prevent microleakage.

Keywords： dental pulp     pulp capping     self-etching adhesives     antibacterial components    

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Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer

Jacqueline CONCHA, Caroline WEINSTEIN, María Elvira Zú?IGA

Frontiers of Chemical Science and Engineering 2013, Volume 7, Issue 4,   Pages 482-489 doi: 10.1007/s11705-013-1342-5

Abstract: In the last years, sugar beet pectins have been the subject of several investigations involving extraction methodologies, chemical composition and functional properties. The structure of pectins, which depends on the extraction method, is decisive in their capacity to induce apoptosis on several cancer cell lines like colon, prostate and breast. In this work, sugar beet pectin extraction was performed in the following steps: lipid extraction with hexane, removal of soluble complex carbohydrates and proteins, and enzymatic treatment with amyloglucosidase, protease, and pectinase. The enzymatic treatment was carried out with Rohapect DA6L under the following conditions: 50°C, pH 4.0, 2% enzyme/substrate (E/S) ratio, 15 h, and a solid to liquid ratio of 1 ∶ 10. The pectic extract showed a degree of polymerization (DP) profile of 55.8% with DP≥7; 4.9% with DP6; 5.8% between DP2 and DP6 ; 4.7% with DP2; and 28.8% with DP1. The pectic extract was examined for its antiproliferative activity on the MCF-7 breast cancer cell line. At a concentration range of 12.5–25 mg/mL the pectic extract killed 80.6% of the cells, exhibiting a higher antiproliferative activity than 4-hydroxytamoxifen (4-OHT), a classical anticancer drug, which killed 56.5% of the cells.

Keywords： pectic extracts     antiproliferative activity     breast cancer     enzymatic treatment    

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Migration of manganese and iron during the adsorption-regeneration cycles for arsenic removal

Fangfang CHANG, Jiuhui QU, Xu ZHAO, Wenjun LIU, Kun WU

Frontiers of Environmental Science & Engineering 2011, Volume 5, Issue 4,   Pages 512-518 doi: 10.1007/s11783-011-0372-9

Abstract: Fe-Mn binary oxide incorporated into porous diatomite (FMBO-diatomite) was prepared in situ and regenerated in a fixed-bed column for arsenite [As(III)] and arsenate [As(V)] removal. Four consecutive adsorption cycles were operated under the following conditions: Initial arsenic concentration of 0.1 mg·L , empty bed contact time of 5 min, and pH 7.0. About 3000, 3300, 3800, and 4500 bed volumes of eligible effluent (arsenic concentration≤0.01 mg·L ) were obtained in four As(III) adsorption cycles; while about 2000, 2300, 2500, and 3100 bed volumes of eligible effluent were obtained in four As(V) adsorption cycles. The dissection results of FMBO-diatomite fixed-bed exhibited that small amounts of manganese and iron were transferred from the top of the fixed-bed to the bottom of the fixed-bed during As(III) removal process. Compared to the extremely low concentration of iron (<0.01 mg·L ), the fluctuation concentration of Mn in effluent of the As(III) removal column was in a range of 0.01–0.08 mg·L . The release of manganese suggested that manganese oxides played an important role in As(III) oxidation. Determined with the US EPA toxicity characteristic leaching procedure (TCLP), the leaching risk of As(III) on exhausted FMBO-diatomite was lower than that of As(V).

Keywords： arsenic     adsorption     filtration     regeneration     fixed-bed    

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biomaterial transplantation and genetic enhancement of intrinsic growth capacities to promote CNS axon regeneration

Bin Yu, Xiaosong Gu

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 131-137 doi: 10.1007/s11684-018-0642-z

Abstract: The inhibitory environment that surrounds the lesion site and the lack of intrinsic regenerative capacity of the adult mammalian central nervous system (CNS) impede the regrowth of injured axons and thereby the reestablishment of neural circuits required for functional recovery after spinal cord injuries (SCI). To circumvent these barriers, biomaterial scaffolds are applied to bridge the lesion gaps for the regrowing axons to follow, and, often by combining stem cell transplantation, to enable the local environment in the growth-supportive direction. Manipulations, such as the modulation of PTEN/mTOR pathways, can also enhance intrinsic CNS axon regrowth after injury. Given the complex pathophysiology of SCI, combining biomaterial scaffolds and genetic manipulation may provide synergistic effects and promote maximal axonal regrowth. Future directions will primarily focus on the translatability of these approaches and promote therapeutic avenues toward the functional rehabilitation of patients with SCIs.

Keywords： spinal cord injury     biomaterial     extrinsic barrier     intrinsic regeneration capacity    

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Synthesis of hydroxymethylfurfural and furfural from hardwood and softwood pulp using ferric sulphate

Agneev Mukherjee, Guillermo Portillo-Perez, Marie-Josée Dumont

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 3,   Pages 531-542 doi: 10.1007/s11705-019-1814-3

Abstract: It was found that for hardwood pulp, the use of ferric sulphate alone gave a maximum HMF yield of 31.6Softwood pulp was harder to depolymerise than hardwood, with a yield of 28.7% obtained using ferric sulphate

Keywords： 5-hydroxymethylfurfural     hardwood     softwood     ferric sulphate     biorefinery    

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Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 401-413 doi: 10.1007/s11684-011-0161-7

Abstract: science and tissue engineering technology, is considered as an ideal alternative strategy for bone regenerationThe preclinical animal models for bone regeneration and the key translational points to clinical success

Keywords： bone regeneration     animal models     translational strategies     oral and maxillofacial region    

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Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Frontiers in Energy 2007, Volume 1, Issue 1,   Pages 85-90 doi: 10.1007/s11708-007-0008-8

Abstract: In this paper regeneration and energy storage characteristics were studied theoretically and experimentallyTwo criterion equations for heat and mass transfer in the regeneration process were obtained.The main factors that influence the regeneration process were analyzed.

Keywords： desiccant air-conditioning     regeneration process     air-conditioning system     energy     regeneration    

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Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 2,   Pages 265-278 doi: 10.1007/s11465-019-0571-9

Abstract: To improve the fuel economy of rail vehicles, this study presents the feasibility of using power regenerating dampers (PRDs) in the primary suspension systems of railway vehicles and evaluates the potential and recoverable power that can be obtained. PRDs are configured as hydraulic electromagnetic-based railway primary vertical dampers and evaluated in parallel and series modes (with and without a viscous damper). Hydraulic configuration converts the linear behavior of the track into a unidirectional rotation of the generator, and the electromagnetic configuration provides a controllable damping force to the primary suspension system. In several case studies, generic railway vehicle primary suspension systems that are configured to include a PRD in the two configuration modes are modeled using computer simulations. The simulations are performed on measured tracks with typical irregularities for a generic UK passenger route. The performance of the modified vehicle is evaluated with respect to key performance indicators, including regenerated power, ride comfort, and running safety. Results indicate that PRDs can simultaneously replace conventional primary vertical dampers, regenerate power, and exhibit desirable dynamic performance. A peak power efficiency of 79.87% is theoretically obtained in series mode on a top-quality German Intercity Express track (Track 270) at a vehicle speed of 160 mile/h (~257 km/h).

Keywords： railway vehicle     primary damper     power regeneration     ride comfort     running safety    

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Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 237-249 doi: 10.1007/s11684-016-0464-9

Abstract: In this regard, Wnt and Notch signaling has gained increased research attention in hair cell regenerationpossibilities of controlling these pathways with the hair cell fate determiner Atoh1 to regulate hair cell regeneration

Keywords： inner ear     cochlea     hair cell     regeneration     Wnt     Notch     signaling pathways    

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Preparation and characteristics of TEMPO-oxidized cellulose nanofibrils from bamboo pulp and their oxygen-barrier

Bozhen Wu, Biyao Geng, Yufei Chen, Hongzhi Liu, Guangyao Li, Qiang Wu

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 4,   Pages 554-563 doi: 10.1007/s11705-017-1673-8

Abstract: Bleached bamboo kraft pulp was pretreated by 2,2,6,6-tetramethylpiperidine-1-oxy radical (TEMPO)-mediatedAnd the presence of hemicellulose in the pulp is favorable to TEMPO oxidization.After the oxidization, the native cellulose I crystalline structure and crystal size of bamboo pulp areTherefore, inexpensive and abundant bamboo pulp would be a promising starting material to isolate cellulose

Keywords： bamboo     TEMPO     cellulose nanofibrils     oxygen barrier    

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Electro-assisted regeneration of ion exchange resins

LIU Zhigang, WANG Ying, LI Yansheng, CHANG Hui

Frontiers of Environmental Science & Engineering 2008, Volume 2, Issue 4,   Pages 410-414 doi: 10.1007/s11783-008-0069-x

Abstract: Electro-assisted regeneration (EAR) for the mixed bed of strongly acidic cation and weakly basic anionExperimental results showed that the efficiency of resin regeneration was strictly dependent on the voltage, regeneration time, and feed regenerant flow rate.The desalination and regeneration reaction mechanisms of the mixed resins indicated the regeneration

Keywords： effluent volume     acidic     three-compartment     weakly     exchange    

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Sulfidation/regeneration multicycle testing of nickel-modified ZnFe

Wei LI, Jinju GUO, Jiejie HUANG, Jiaotao ZHAO

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 4,   Pages 435-440 doi: 10.1007/s11705-010-0506-9

Abstract: desulphurization reactivity, mechanical strength, ability to regenerate, and stability to endure many sulfidation-regenerationmeasured in a fixed-bed reactor at middle temperature of 300°C (sulfidation temperature) and 500°C (regenerationnickel-modified ZnFe O keeps high reactivity and structural stability in the multicycle testing of sulfidation/regeneration

Keywords： hot gas desulphurization     nickel-modified ZnFe2O4     sulfidation/regeneration    

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Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Frontiers of Medicine 2019, Volume 13, Issue 2,   Pages 160-188 doi: 10.1007/s11684-018-0629-9

Abstract: Effective therapies for bone regeneration primarily require the coordinated combination of innovativeovercome these shortcomings and facilitate the clinical application of these techniques to enhance bone regenerationdiscuss the challenges and perspectives that may propel the direction of future clinical delivery in bone regeneration

Keywords： bone tissue engineering     stem cell     bone scaffold     growth factor     bone regeneration    

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Tissue regeneration: dream, hope and challenge

Ding Xiaobing

Strategic Study of CAE 2009, Volume 11, Issue 10,   Pages 122-128

Abstract:

Tissue regeneration is the research focus in the fields of biology andIn this paper, some very important aspects dealing with the tissue repair and regeneration were reviewed

Keywords： injury     tissue     repair     regeneration    

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Title Author Date Type Operation

Dental stem cell and dental tissue regeneration

Qiming Zhai, Zhiwei Dong, Wei Wang, Bei Li, Yan Jin

Journal Article

Self-etching adhesives: possible new pulp capping agents to vital pulp therapy

Chun CUI, Xiu-Neng ZHOU, Wei-Min CHEN

Journal Article

Production of pectic extracts from sugar beet pulp with antiproliferative activity on a breast cancer

Jacqueline CONCHA, Caroline WEINSTEIN, María Elvira Zú?IGA

Journal Article

Migration of manganese and iron during the adsorption-regeneration cycles for arsenic removal

Fangfang CHANG, Jiuhui QU, Xu ZHAO, Wenjun LIU, Kun WU

Journal Article

biomaterial transplantation and genetic enhancement of intrinsic growth capacities to promote CNS axon regeneration

Bin Yu, Xiaosong Gu

Journal Article

Synthesis of hydroxymethylfurfural and furfural from hardwood and softwood pulp using ferric sulphate

Agneev Mukherjee, Guillermo Portillo-Perez, Marie-Josée Dumont

Journal Article

Bone regeneration by stem cell and tissue engineering in oral and maxillofacial region

Zhiyuan Zhang

Journal Article

Investigation on regeneration and energy storage characteristics of a solar liquid desiccant air-conditioning

SHI Mingheng, DU Bin, ZHAO Yun

Journal Article

Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Journal Article

Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea

Muhammad Waqas,Shasha Zhang,Zuhong He,Mingliang Tang,Renjie Chai

Journal Article

Preparation and characteristics of TEMPO-oxidized cellulose nanofibrils from bamboo pulp and their oxygen-barrier

Bozhen Wu, Biyao Geng, Yufei Chen, Hongzhi Liu, Guangyao Li, Qiang Wu

Journal Article

Electro-assisted regeneration of ion exchange resins

LIU Zhigang, WANG Ying, LI Yansheng, CHANG Hui

Journal Article

Sulfidation/regeneration multicycle testing of nickel-modified ZnFe

Wei LI, Jinju GUO, Jiejie HUANG, Jiaotao ZHAO

Journal Article

Current advances for bone regeneration based on tissue engineering strategies

Rui Shi, Yuelong Huang, Chi Ma, Chengai Wu, Wei Tian

Journal Article

Tissue regeneration: dream, hope and challenge

Ding Xiaobing

Journal Article